Did India have the world's largest outbreak of poliomyelitis associated with injections of adjuvanted DPT?

نویسنده

  • T J John
چکیده

The recent report of an explosive outbreak of poliomyelitis in an orphanage in Delhi(l) and the subsequent correspondence(2,3) have highlighted the phenomenon of 'provocation poliomyelitis'. If an intramuscular injection is given during silent poliovirus infection, paralysis may set in within a day or two. In a community in which poliovirus circulation is intensive, children are at increased risk of developing paralysis for one month after the injection; only those children who happen to get infected during that interval are at risk. The more intensive the endemicity of polioviruses, the greater the probability of provocation poliomyelitis.

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عنوان ژورنال:
  • Indian pediatrics

دوره 35 1  شماره 

صفحات  -

تاریخ انتشار 1998